Fracking chemicals and reproductive abnormalities in mice - GoMarcellusShale.com2024-03-28T21:24:14Zhttps://gomarcellusshale.com/forum/topics/fracking-chemicals-and-reproductive-abnormalities-in-mice?id=2274639%3ATopic%3A772539&feed=yes&xn_auth=noAll you need to know about th…tag:gomarcellusshale.com,2018-02-12:2274639:Comment:7726442018-02-12T12:08:34.214ZBarry Dhttps://gomarcellusshale.com/profile/BarryDyngel
<p>All you need to know about this bogus study is this,</p>
<p>The team of researchers was turned down for funding by the National Institutes for Health</p>
<p>because it was determined that their work was not good enough for funding. Why?</p>
<p>Because the teams previous work had been shown to be biased and lacking in sound</p>
<p>scientific methodology. Further, one of the lead researchers regularly speaks publicly</p>
<p>against oil and gas development.</p>
<p>In turn they reached out to…</p>
<p>All you need to know about this bogus study is this,</p>
<p>The team of researchers was turned down for funding by the National Institutes for Health</p>
<p>because it was determined that their work was not good enough for funding. Why?</p>
<p>Because the teams previous work had been shown to be biased and lacking in sound</p>
<p>scientific methodology. Further, one of the lead researchers regularly speaks publicly</p>
<p>against oil and gas development.</p>
<p>In turn they reached out to well known anti-fracking-activists Josh Fox, Mark Ruffalo and</p>
<p>Yoko Ono.</p>
<p>Finally, Paul spends a great deal of time citing concentrations found in the study as if those</p>
<p>concentrations might be found in sources of water consumed by humans. First problem:</p>
<p>it is not the concentrations that are important, it's the dosage, humans rarely consume as</p>
<p>much water as was fed to the mice. Next: it has never been shown that the chemicals cited</p>
<p>have been found in any unsafe quantity in drinking water anywhere. The mice were force fed the</p>
<p>water, thus raining the amount of chemicals ingested.</p>
<p>In in other words, this teams work has once again been shown to be shoddy and lacking in any</p>
<p>in scientific methodology and has been completely debunked once again (this is the third time).</p>
<p>Just more Chicken Little stuff.</p>
<p>The Sky Is Falling! The Sky is Falling! The Sky Is Falling</p> “Kassotis et al. then evaluat…tag:gomarcellusshale.com,2018-02-12:2274639:Comment:7723692018-02-12T05:33:42.512ZPaul Heckberthttps://gomarcellusshale.com/profile/PaulHeckbert
<p class="p1">“Kassotis et al. then evaluated the <strong>effects of a 23-chemical mixture of UOG [unconventional oil & gas] chemicals (UOG-MIX) on male mice</strong> ... Male mice exposed to environmentally relevant doses of UOG-MIX during prenatal development displayed … <strong>decreased sperm counts; … alterations to the weight of additional organs including the heart and thymus</strong> (13). …</p>
<p class="p2"></p>
<p class="p1">Importantly, <strong>the effects that were observed in…</strong></p>
<p class="p1">“Kassotis et al. then evaluated the <strong>effects of a 23-chemical mixture of UOG [unconventional oil & gas] chemicals (UOG-MIX) on male mice</strong> ... Male mice exposed to environmentally relevant doses of UOG-MIX during prenatal development displayed … <strong>decreased sperm counts; … alterations to the weight of additional organs including the heart and thymus</strong> (13). …</p>
<p class="p2"></p>
<p class="p1">Importantly, <strong>the effects that were observed in this study occurred at low doses</strong>; the two lowest dose groups (MIX-3 and MIX-30) are <strong>equivalent to the concentrations measured in drinking water in regions experiencing drilling</strong> while the highest dose group (MIX-3000) is equivalent to the concentrations of many UOG-MIX components measured in industry wastewater.”</p>
<p class="p2"></p>
<p class="p1">The fracking chemicals tested:</p>
<ul>
<li class="p1">1,2,4-Trimethylbenzene</li>
<li class="p1">2-(2-Methoxyethoxy) ethanol</li>
<li class="p1">2-Ethylhexanol</li>
<li class="p1">2-Methyl-4-isothiazolin-3-one</li>
<li class="p1">Acrylamide</li>
<li class="p1">Benzene</li>
<li class="p1">Bronopol</li>
<li class="p1">Cumene</li>
<li class="p1">Diethanolamine</li>
<li class="p1">Ethoxylated nonylphenol</li>
<li class="p1">Ethoxylated octylphenol</li>
<li class="p1">Ethylbenzene</li>
<li class="p1">Ethylene glycol</li>
<li class="p1">Ethylene glycol monobutyl ether</li>
<li class="p1">Naphthalene</li>
<li class="p1">N,n-dimethylformamide</li>
<li class="p1">Phenol</li>
<li class="p1">Propylene glycol</li>
<li class="p1">Sodium tetraborate decahydrate</li>
<li class="p1">Styrene</li>
<li class="p1">Toluene</li>
<li class="p1">Triethylene glycol</li>
<li class="p1">Xylenes</li>
</ul>
<p class="p1">Advance version of the research paper</p>
<p class="p1">“Prenatal exposure to unconventional oil and gas operation chemical mixtures altered mammary gland development in adult female mice”</p>
<p class="p1">[but note: Advance Articles are PDF versions of manuscripts … not yet copyedited]</p>
<p class="p2">pages 1-17: <a href="http://storage.ning.com/topology/rest/1.0/file/get/35535471?profile=original" target="_self">mouse_fracking_p1-17.pdf</a></p>
<p class="p2">pages 18-22 (figures): <a href="http://storage.ning.com/topology/rest/1.0/file/get/35535538?profile=original" target="_self">mouse_fracking_p18-22_150dpi.pdf</a></p>
<p class="p2"></p>
<p class="p1">(13) Endocrine-Disrupting Activity of Hydraulic Fracturing Chemicals and Adverse Health Outcomes After Prenatal Exposure in Male Mice, <a href="https://academic.oup.com/endo/article/156/12/4458/2422671">https://academic.oup.com/endo/article/156/12/4458/2422671</a></p> I have a problem with this...…tag:gomarcellusshale.com,2018-02-11:2274639:Comment:7725712018-02-11T20:57:52.971ZBullfrexhttps://gomarcellusshale.com/profile/delmardave
<p>I have a problem with this....the operative words in the statement below being <em><strong>similar</strong></em> and <em><strong>might.....</strong></em></p>
<p><em><strong>Nagel and colleagues used four different doses —<span> </span><span>the two lowest doses were similar to what you might find in drinking water in areas near oil and gas operations,</span></strong></em></p>
<p>So have they actually found these concentrations in drinking water near O&G operations? If so, were the…</p>
<p>I have a problem with this....the operative words in the statement below being <em><strong>similar</strong></em> and <em><strong>might.....</strong></em></p>
<p><em><strong>Nagel and colleagues used four different doses —<span> </span><span>the two lowest doses were similar to what you might find in drinking water in areas near oil and gas operations,</span></strong></em></p>
<p>So have they actually found these concentrations in drinking water near O&G operations? If so, were the wells/drinking water chemicals traced back to a particular well pad? If not, why not?</p>
<p>As usual, the entire study is shrouded in ambiguities and innuendo, financed by the Left to further their Green agenda.</p>
<p></p> Excessive road salt can rust…tag:gomarcellusshale.com,2018-02-11:2274639:Comment:7725642018-02-11T14:24:57.561Zpalefacehttps://gomarcellusshale.com/profile/paleface
<p>Excessive road salt can rust your car or truck in a couple years.Do you think that effects the mice.</p>
<p>Excessive road salt can rust your car or truck in a couple years.Do you think that effects the mice.</p> About the doses used in the e…tag:gomarcellusshale.com,2018-02-11:2274639:Comment:7726382018-02-11T06:02:13.650ZPaul Heckberthttps://gomarcellusshale.com/profile/PaulHeckbert
<p>About the doses used in the experiments:</p>
<p>"Nagel and colleagues used four different doses —<span> </span><span><strong>the two lowest doses were similar to what you might find in drinking water in areas near oil and gas operations, </strong>and the higher doses were comparable to wastewater puddles on work sites near fracking, </span>said senior author Laura Vandenberg, a researcher and assistant professor at the University of Massachusetts–Amherst School of Public Health & Health…</p>
<p>About the doses used in the experiments:</p>
<p>"Nagel and colleagues used four different doses —<span> </span><span><strong>the two lowest doses were similar to what you might find in drinking water in areas near oil and gas operations, </strong>and the higher doses were comparable to wastewater puddles on work sites near fracking, </span>said senior author Laura Vandenberg, a researcher and assistant professor at the University of Massachusetts–Amherst School of Public Health & Health Sciences.</p>
<p>They saw effects on all exposed mice.</p>
<h2><strong>“Even at low doses we’re seeing lesions in the mammary gland,”</strong><span> </span>Vandenberg said.</h2>
<p>... The 23 chemicals in the mixture are all known endocrine disruptors and have previously been show to either mimic or interfere with certain hormones."</p> Sounds like they came up with…tag:gomarcellusshale.com,2018-02-11:2274639:Comment:7723572018-02-11T05:31:15.791Zpalefacehttps://gomarcellusshale.com/profile/paleface
<p>Sounds like they came up with a new mouse trap. Good job frackers keep up the good work.</p>
<p>Sounds like they came up with a new mouse trap. Good job frackers keep up the good work.</p> Well....there you have it....…tag:gomarcellusshale.com,2018-02-11:2274639:Comment:7725532018-02-11T00:21:09.160ZBullfrexhttps://gomarcellusshale.com/profile/delmardave
<p>Well....there you have it....definitive proof, because 'some of the mice developed precancerous lesions'....my question....how many is 'some'? One, fifty, three hundred? What percentage of mice showed symptoms?</p>
<p>How many mice were in this study, and, more importantly, did they ALL sign consent forms to be in this study?</p>
<p>My next email is going directly to PETA!!</p>
<p></p>
<p>Well....there you have it....definitive proof, because 'some of the mice developed precancerous lesions'....my question....how many is 'some'? One, fifty, three hundred? What percentage of mice showed symptoms?</p>
<p>How many mice were in this study, and, more importantly, did they ALL sign consent forms to be in this study?</p>
<p>My next email is going directly to PETA!!</p>
<p></p> This is terrible news for any…tag:gomarcellusshale.com,2018-02-10:2274639:Comment:7724562018-02-10T23:16:39.733ZBretthttps://gomarcellusshale.com/profile/Brettonmerryman
<p>This is terrible news for anyone who drinks mouse milk!</p>
<p>This may very well be the end to fracking as we know it!</p>
<p>Even our pet hamsters may not be safe.</p>
<p>This is terrible news for anyone who drinks mouse milk!</p>
<p>This may very well be the end to fracking as we know it!</p>
<p>Even our pet hamsters may not be safe.</p> Not to worry. Once we have m…tag:gomarcellusshale.com,2018-02-10:2274639:Comment:7724462018-02-10T11:57:18.590ZDanhttps://gomarcellusshale.com/profile/Dang
<p>Not to worry. Once we have more windmills in place to chop up more birds of prey, the mice population will thrive once again. </p>
<p>Not to worry. Once we have more windmills in place to chop up more birds of prey, the mice population will thrive once again. </p> I totally agree with Heckbert…tag:gomarcellusshale.com,2018-02-10:2274639:Comment:7724412018-02-10T00:11:03.344ZDavid Allen Lillyhttps://gomarcellusshale.com/profile/DavidAllenLilly
<p>I totally agree with Heckbert and share his deep concern for the reproductive ability of mice everywhere as I have already noticed the great American mouse shortage.</p>
<p>I totally agree with Heckbert and share his deep concern for the reproductive ability of mice everywhere as I have already noticed the great American mouse shortage.</p>